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239 ANTI-TUMOR ACTIVITY OF HISTONE DEACETYLASE INHIBITOR FK228 (DEPSIPEPTIDE) FOR HUMAN PROSTATE CANCER CELLS

✍ Scribed by W.C. Chen; M.T. Lai; F.J. Tsai; T.Y. Lin; C.C. Yang


Book ID
119617571
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
316 KB
Volume
6
Category
Article
ISSN
1569-9056

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## Abstract Inhibition of histone deacetylase (HDAC) is a novel strategy for the treatment of leukemias via restoration of aberrantly silenced genes. In this study, we conducted a detailed analysis of anti‐leukemic effects of an HDAC inhibitor (HDI), depsipeptide (FK228), using myeloid leukemia cel