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2,3,7,8-Tetrachlorodibenzo-p-dioxin increases reactive oxygen species production in human endothelial cells via induction of cytochrome P4501A1

✍ Scribed by P.G. Kopf; M.K. Walker


Book ID
113924700
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
895 KB
Volume
245
Category
Article
ISSN
0041-008X

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## Abstract 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) was classified by the International Agency for Research on Cancer as a carcinogen in humans. It acts through an aryl hydrocarbon receptor‐mediated mechanism, inducing the transcription of numerous genes, including various cytochrome P450s (CYPs