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2,3-Oxidosqualene, an Intermediate in the Biological Synthesis of Sterols from Squalene 1

✍ Scribed by Corey, E. J.; Russey, William E.; de Montellano, Paul R. Ortiz


Book ID
120664733
Publisher
American Chemical Society
Year
1966
Tongue
English
Weight
270 KB
Volume
88
Category
Article
ISSN
0002-7863

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## Abstract __N__‐Chloromethylphthalimide 1 and the potassium salt of pyrrole gave __N__‐(pyrrol‐1‐ylmethyl)pbthalimide 2. Reduction of 2 led to the hydroxyisoindolone 3. This hydroxylactam cyclized under acidic conditions to lead to a pyrroloimidazoloisoindolone 4 __via__ an acyliminium ion. Trans