Semisynthesis of 3′(2′)-O-(Aminoacyl)-tR
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Zhiyong Cui; Biliang Zhang
📂
Article
📅
2007
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John Wiley and Sons
🌐
German
⚖ 217 KB
## Abstract An efficient synthesis of (3′‐terminally) 3′(2′)‐__O__‐aminoacylated pCpA derivatives is described, which could lead to the production of (aminoacyl)‐tRNAs following T4 RNA ligase mediated ligation. The tetrahydrofuranyl (thf) group was used as a permanent protective group for the 2′‐OH