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23. High affinity binding of glucocorticoids, estrogens and androgens in cytosols of human mammary carcinomas

✍ Scribed by F.A.G. Teulings; R.E. Treurniet; J. Alexieva-Figusch; J. Blonk-van der Wijst; H.A. van Gilse


Book ID
118925265
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
197 KB
Volume
6
Category
Article
ISSN
0022-4731

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## Abstract The relative ability of the antiestrogen, tamoxifen, and its monohydroxy and desmethyl metabolites to displace tritiated estradiol from estrogen receptors isolated from human breast carcinoma was determined. 4‐Hydroxytamoxifen binds to the estrogen receptor with affinity equal to estrad