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2,3-Disubstituted Indoles through the Palladium-Catalyzed Reaction of Aryl Chlorides with o-Alkynyltrifluoroacetanilides

✍ Scribed by Sandro Cacchi; Giancarlo Fabrizi; Antonella Goggiamani


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
90 KB
Volume
348
Category
Article
ISSN
1615-4150

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## Abstract An efficient and practical synthetic method has been developed for the preparation of symmetrical diarylacetylenes from the direct reaction of aryl chlorides with 2‐methyl‐3‐butyn‐2‐ol catalyzed by palladium(II) chloride‐bis(tricyclohexylphosphine) [PdCl~2~(PCy~3~)~2~] under mild reacti