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229 Alternative Splicing of Kruppel-like Factor 4 Plays a Role in Colorectal Tumorigenesis

✍ Scribed by Baek, S.; Bahn, J.; Lee, S.; Smolensky, D.; Yoon, J.

Book ID: 122715010
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 62 KB
Volume: 48
Category: Article
ISSN: 0959-8049
DOI: 10.1016/S0959-8049(12)72027-0

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## Abstract Deregulation of protein synthesis plays a critical role in cell transformation. Several translation initiation factors (eIFs) have been implicated in malignant transformation; thus, suppression of eIFs could be a potential cancer therapy if cancer cells are selectively killed without da