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2,2′,4,6,6′-Pentachlorobiphenyl Induces Apoptosis in Human Monocytic Cells

✍ Scribed by Kum-Joo Shin; Sun Sik Bae; You-A Hwang; Jeong Kon Seo; Sung Ho Ryu; Pann-Ghill Suh


Book ID
112267226
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
166 KB
Volume
169
Category
Article
ISSN
0041-008X

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TrkA induces differentiation but not apo
✍ Beth R. Pflug; Anna Maria Colangelo; Carlo Tornatore; Italo Mocchetti 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 252 KB

## Abstract Nerve growth factor (NGF) binds to the TrkA tyrosine kinase and the p75 neurotrophin receptors. Depending upon which receptor is activated, NGF can induce differentiation or apoptosis. C6‐2B glioma cells express the p75 receptor, but NGF decreases their growth only when TrkA is introduc