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2,2,4-Trimethylpentane-induced nephrotoxicity: I. Metabolic disposition of TMP in male and female Fischer 344 rats

✍ Scribed by Michel Charbonneau; Edward A. Lock; Josef Strasser; Michael G. Cox; Max J. Turner; James S. Bus

Book ID
113206923
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
971 KB
Volume
91
Category
Article
ISSN
0041-008X

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## Abstract The agricultural fungicide __N__‐(3,5‐dichlorophenyl)succinimide (NDPS) is a more potent nephrotoxicant in female rats than in males. Similarly, nephrotoxicant NDPS metabolites studied to date in male and female rats have also demonstrated gender differences, being twice as potent as ne