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224 Molecular targeting of malignant pleural mesothelioma by c-Met and ROS modulation

✍ Scribed by Jagadeeswaran, R.; Zumba, O.; Kindler, H.L.; Salgia, R.


Book ID
118573907
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
48 KB
Volume
54
Category
Article
ISSN
0169-5002

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## Abstract NK4 exhibits two distinct biological actions: antagonistic inhibition of hepatocyte growth factor (HGF) through binding to the Met/HGF receptor, and antiangiogenic action through binding to perlecan. Here, the anti‐tumor effect of NK4 on malignant pleural mesothelioma was investigated.