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[2+2+2]-Cycloaddition of 4-Hydroxy-Substituted Enediynes to 2-Hydroxy-Substituted Decahydrophenanthrenes

โœ Scribed by Ulrich Groth; Norbert Richter; Aris Kalogerakis


Book ID
102170015
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
136 KB
Volume
2003
Category
Article
ISSN
1434-193X

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โœ Teodozyj Kolasa; Marvin J. Miller ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 189 KB

A short chemical process is described for the synthesis of optically active 3y roxy-4-alkoxycarbonyl-Z-azetidinones (R-lactams) from L-tartaric acid. Tartaric acid is an extremely useful and versatile member of the chiral pool. Since nearly any type of f+hydroxy acid can be converted to a 8-lactam (