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2.210 Determining the benefit of levodopa/carbidopa/entacapone (Stalevo®) on the pharmacokinetic profile of levodopa: a randomized, crossover, multicentre study in patients with Parkinson's disease

✍ Scribed by S. Kaakola; J. Ellmén; R. Marttila; V. Kaasinen; P. Hartikainen; J. Lyytinen; J. Hänninen; K. Korpela; M. Kuoppamäki


Book ID
117752861
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
54 KB
Volume
13
Category
Article
ISSN
1353-8020

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Effect of entacapone, a COMT inhibitor,
✍ V. V. Myllylä; K. A. Sotaniemi; A. Illi; K. Suominen; T. Keränen 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 563 KB

In an open, randomised, cross-over study we investigated the effect of a single 200 mg oral dose of entacapone, a novel catechol-O-methyltransferase (COMT) inhibitor, on the pharmacokinetics and metabolism of levodopa/carbidopa, and on the cardiovascular responses (blood pressure and pulse rate vari