Systematic biochemical analysis of somat
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Chang Long An; Desheng Chen; Nick M. Makridakis
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Article
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2011
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John Wiley and Sons
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English
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DNA polymerase ฮฒ is essential for short-patch base excision repair. We have previously identified 20 somatic pol ฮฒ mutations in prostate tumors, many of them missense. In the current article we describe the effect of all of these somatic missense pol ฮฒ mutations (p.K27N, p.E123K, p.E232K, p.P242R, p