2(1H)-Pyrazinones and 2H-1,4-Oxazin-2-Ones as Synthetic Tools For Other Heterocycles
✍ Scribed by Georges Hoornaert
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 258 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0037-9646
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The reaction of 2(1__H__)‐pyrazinones 1 and 1,2,4‐triazoline‐3,5‐diones 3 was investigated by comparing that of 1 with singlet oxygen. 2(1__H__)‐Pyrazinones 1 reacted in Diels‐Alder fashion with 1,2,4‐triazoline‐3,5‐diones 3 to afford [4+2]‐adducts 4–17 in high yields.
## Abstract Substituted 2‐(benzylamino)‐2__H__‐1,4‐benzoxazin‐3(4__H__)‐ones are unstable under alkaline and acidic conditions, undergoing opening of the benzoxazinone ring. 2‐Bromo‐2__H__‐1,4‐benzoxazin‐3(4__H__)‐ones show similar degradation under alkaline conditions, while replacement of Br at C