2194. Class distinctions in tumorigenic response: Roe, F. J. C. & Grant, G. A. (1970). Inhibition by germ-free status of development of liver and lung tumours in mice exposed neonatally to 7,12-dimethylbenz(a)anthracene: Implications in relation to tests for carcinogenicity. Int. J. Cancer 6, 133

Inhibition by germ-free status of develo

Inhibition by germ-free status of development of liver and lung tumours in mice exposed neonatally to 7,12-dimethylbenz(A)anthracene: Implications in relation to tests for carcinogenicity

✍ F. J. C. Roe; G. A. Grant 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 906 KB

## Abstract Germ‐free (GF) status significantly “protected” male C3H mice from the early (before 40 weeks) development of liver‐cell tumours in response to 7,12‐dimethylbenz(a)anthracene (DMBA) given shortly after birth. GF status significantly protected C3H mice of both sexes from the early develo