Up-regulation of MRP4 and down-regulatio
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Xing-Xiang Peng; Zhi Shi; Vijaya L. Damaraju; Xiao-Cong Huang; Gary D. Kruh; Hsi
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Article
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2008
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Elsevier Science
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English
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To investigate the mechanism of cellular resistance to 6-MP, we established a 6-MP resistant cell line (CEM-MP5) by stepwise selection of the human T-lymphoblastic leukemia cell line (CEM). CEM-MP5 cells were about 100-fold resistant to 6-MP compared with parental CEM cells. Western blot analysis de