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21. Pteridines. Part I. An unambiguous synthesis of 7 : 8-dihydro-6-hydroxypteridines

✍ Scribed by Boon, W. R. ;Jones, W. G. M. ;Ramage, G. R.


Book ID
124092209
Publisher
The Royal Society of Chemistry
Year
1951
Weight
679 KB
Category
Article
ISSN
0368-1769

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Pteridines. Part XLI. Synthesis and prop
✍ Walter HΓΌbsch; Wolfgang Pfleiderer πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 German βš– 344 KB

The first representative of the &substituted 4-thiolumazine series has been synthesized. In a sequence of reactions, 4,6-dichloropyrimidin-2-( 1 H)-one (1) is first converted into 4-chloro-6-(methylamino)pyrimidin-2( 1H)one (6), then the Cl-atom displaced by the thioxo group ( +7) followed by a coup