Immunohistochemical analysis of integrin
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Regina Max; Roland R.C.M. Gerritsen; Peet T.G.A. Nooijen; Simon L. Goodman; Arne
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Article
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1997
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John Wiley and Sons
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French
⚖ 141 KB
Expression of the alpha vbeta3 integrin is upregulated on sprouting endothelia. Systemic application of antibody or peptidic inhibitors of alpha vbeta3 function disrupts tumor angiogenesis and reduces growth and invasiveness of human tumors in animal models. We systematically investigated alpha vbet