Secreted phospholipase A2 potentiates gl
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Mark A. DeCoster; Gerard Lambeau; Michel Lazdunski; Nicolas G. Bazan
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Article
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2002
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John Wiley and Sons
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English
β 762 KB
## Abstract Secreted phospholipases A~2~ (sPLA~2~s) modulate neuronal survival and neurotransmitter release. Here we show that sPLA~2~ (group III) synergistically increases glutamateβinduced cell death and intracellular calcium ([Ca^2+^]~i~) in cultured primary cortical and hippocampal neurons. Whe