The exposure of 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPOL) to hydroxyl radical ((.)OH) led to the appearance of a new triplet ESR signal along with a reduction in the intensity of the TEMPOL signal. The observed spectrum was in good agreement with the spectrum simulated with 4-oxo-2,2,6
2-(Tert-butylsulfonyl)-ethyl 4-(2,2,6,6-tetramethylpiperidine-1-oxyl) phosphoromorpholidite, a spin-labeled phosphitylating reagent
β Scribed by C. A. A. Claesen; C. J. M. Daemen; G. I. Tesser
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 133 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0165-0513
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Spin l a b e l e d drugs can be u t i l i z e d f o r innnunoassays and determining t h e f r a c t i o n o f f r e e drug i n serum. To improve t h e sensit i v i t y we have synthesized t r i a c e t ~n a m i n e -~~N -d ~? by c y c l i z a t i o n o f phorone-d14 w i t h l5ND,. Phorone-d was obta
Amination of 3-carboxymethyl-1-oxyl-2,2,6,6-tetramethyl-4-piperidone with (R)-a-methylbenzylamine, NaBH 3 CN reduction of the resulting enamine and removal of the chiral auxiliary from the separated diastereoisomers, led to enantiomerically pure (3S,4S) and (3R,4R) methyl 4-amino-1-oxyl-2,2,6,6-tetr
Stable isotope substituted spin labels increase t&e resolution and sensitivity of EPR measurements. An improved synthesis of N-(l-oxy1-2,2,6,6-tetramethyl-4-piperidiny1)maleimide has been devised and utilized. This improved synthesis is accomplished in five steps instead of the normally required sev