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2-Phenyl isopropyl and t-butyl trichloroacetimidates: Useful reagents for ester preparation of N-protected amino acids under neutral conditions

✍ Scribed by Josiane Thierry; Chongwei Yue; Pierre Potier


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
197 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


2-Phenylisopropyl and t-butyl trichloroacetamidates I and 2 are useful reagents for the esterification of N-protected aminoacids under mild neutral conditions. In the case of hydroxylcontaining amino acids, dialkylation occurs but no selectivity could be obtained