A series of phenyl-substituted N 6 -phenyladenosines and N 6 -phenyl-5β²-N-ethylcarboxamidoadenosines were synthesized and tested at adenosine receptor subtypes. EC 50 values were determined for cyclic AMP production in CHO cells expressing human A 2B receptors. Binding affinities were determined for
2-(N-Acyl) and 2-N-Acyl-N6-substituted Analogues of Adenosine and Their Affinity at the Human Adenosine Receptor.
β Scribed by Prakash G. Jagtap; Zhiyu Chen; Csaba Szabo; Karl-Norbert Klotz
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 105 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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viscosity the ESR spectrum of ( I ) shows a poorly resolved hyperfine structure (six lines), which we ascribe to a diradical whose exchange energy J is Large compared with the N coupling constant uN["' ( J $ u N ; 4 2 = 5.5 & 1 G); in addition there is the interaction energy of the electrons with th
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract The interaction between human serum albumin (HSA) and N^6^β(2βhydroxyethyl)βadenosine (HEA) was investigated using fluorescence spectroscopy in combination with UV absorption spectroscopy for the first time. The results of spectroscopic measurements suggested that the hydrophobic intera