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2 Mitochondrial and nuclear encoded subunit assembly into Complex I and assembly defects in mitochondrial disease

✍ Scribed by Matthew McKenzie; Michael Lazarou; Christopher J.R. Dunning; Canny Sugiana; David R. Thorburn; Michael T. Ryan

Book ID
116751753
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
68 KB
Volume
7
Category
Article
ISSN
1567-7249

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πŸ“œ SIMILAR VOLUMES

Assembly factors of human mitochondrial
Assembly factors of human mitochondrial complex I and their defects in disease
✍ Matthew Mckenzie; Michael T. Ryan πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 159 KB

## Abstract NADH‐ubiquinone oxidoreductase (complex I) is a large, multimeric enzyme complex involved in the generation of ATP by oxidative phosphorylation. Complex I is comprised of 45 subunits which must be assembled together in a coordinated process to form the mature holoenzyme. In recent years