𝔖 Bobbio Scriptorium
✦   LIBER   ✦

2-methoxyestradiol strongly inhibits human uterine sarcomatous cell growth

✍ Scribed by Frederic Amant; Mona-Liza Lottering; Annie Joubert; Veneesha Thaver; Ignace Vergote; B.G Lindeque

Book ID
114101690
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
396 KB
Volume
91
Category
Article
ISSN
0090-8258

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

2-Methoxyestradiol modulates β-catenin i
2-Methoxyestradiol modulates β-catenin in prostate cancer cells: A possible mediator of 2-methoxyestradiol-induced inhibition of cell growth
✍ Peter J. Van Veldhuizen; Gibanananda Ray; Snigdha Banerjee; Gopal Dhar; Suman Ka 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 235 KB

2-Methoxyestradiol (2-ME 2 ) is a novel anticancer agent because of its ability to potentiate apoptotic cell death and inhibit cancer cell growth and angiogenesis. The modes of action of this agent, however, have not yet been fully elucidated. In our study, we have investigated whether 2-ME2 is able

2-methoxyestradiol blocks cell-cycle pro
2-methoxyestradiol blocks cell-cycle progression at G2/M phase and inhibits growth of human prostate cancer cells
✍ Addanki P. Kumar; Gretchen E. Garcia; Thomas J. Slaga 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB 👁 1 views

## Abstract 2‐Methoxyestradiol (2‐ME), an endogenous metabolite of 17β‐estradiol, is present in human blood and urine. Here we show for the first time that 2‐ME significantly inhibited the growth of normal prostate epithelial cells and androgen‐dependent LNCaP and androgen‐independent DU145 prostat

2-methoxyestradiol inhibits atorvastatin
2-methoxyestradiol inhibits atorvastatin-induced rounding of human vascular smooth muscle cells
✍ Hao Yin; Yu Gui; Xi-Long Zheng 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 451 KB

## Abstract The cardiovascular benefits of statins, including atorvastatin (ATV), have been reported to be gender‐dependent, but the underlying mechanism is unclear. In this study we examine whether estrogen and its metabolite, 2‐methoxyestradiol (2ME), affect the rounding response of human vascula

Mechanism of 2-methoxyestradiol-induced
Mechanism of 2-methoxyestradiol-induced apoptosis and growth arrest in human breast cancer cells
✍ Masayuki Fukui; Bao Ting Zhu 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 496 KB 👁 1 views

## Abstract 2‐Methoxyestradiol, a well‐known nonpolar endogenous metabolite of 17β‐estradiol, has been shown to selectively induce apoptosis in a number of cancer cell lines, but not in normal cells. The mechanism of 2‐methoxyestradiol‐induced apoptosis appears to vary considerably in different cel