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2-Methoxyestradiol and paclitaxel have similar effects on the cell cycle and induction of apoptosis in prostate cancer cells

✍ Scribed by Carlos Perez-Stable

Book ID: 116333588
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 513 KB
Volume: 231
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2005.01.018

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## Abstract **Scope:** Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables such as broccoli. The ability of SFN to inhibit histone deacetylase (HDAC) enzymes may be one mechanism by which it acts as a chemoprevention agent. The ability of a chemopreventive agent to specifica