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(2-Ethoxy­phen­yl)[4-(6-fluoro­benzo[d]isoxazol-3-yl)piperidin-1-yl]methanone

✍ Scribed by Naveen, S. ;Basappa, ;Sridhar, M. A. ;Shashidhara Prasad, J. ;Rangappa, K. S.

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
306 KB
Volume
63
Category
Article
ISSN
1600-5368

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✦ Synopsis

In the title compound, C 21 H 21 FN 2 O 3 , the piperidine ring is in a chair conformation with the substituted benzisoxazole ring system in an equatorial position. An intermolecular C-HÁ Á ÁO interaction is present in the crystal structure.

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The crystal structure of the title compound, C~17~H~15~FN~2~O~2~, was determined as part of a study of the biological activity of pyridine-substituted isoxazole derivatives as mitogen-activated protein kinase (MAPK) inhibitors. In the crystal structure of the title compound, the compound exists in t