2-(diphenylphosphinoyl) pyrrolidines; versatile reagents for the synthesis of heterocyclic enamines and enamides.
β Scribed by B.H. Bakker; D.S. Tjin A-Lim; A. van der Gen
- Book ID
- 104233778
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 188 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
A method is described for the preparation of N-substituted 2-(diphenylphosphinoyl) pyrrolidines. Application of these phosphine oxides in the Horner-Wittig reaction affords heterocyclic enamines and enamides in good yields.
π SIMILAR VOLUMES
Cyclic as well as acyclic ketones, both saturated and a,b-unsaturated, can be converted into their homologous enamines by Horner-Wittig reaction with g-methyl-L-anilinomethyl diphenylphosphine oxide (3). Enamines are highly valued intermediates in organic synthesis. They react with a large variety
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