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2-Cyanoacrylates in the conjugate addition of trifluoroacetic acid and nucleophilic reagents

โœ Scribed by G. D. Kolomnikova; T. O. Krylova; I. V. Chernoglazova; P. V. Petrovskii; Yu. G. Gololobov


Book ID
112387832
Publisher
Springer
Year
1993
Tongue
English
Weight
278 KB
Volume
42
Category
Article
ISSN
1573-9171

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Diastereoselection in the nucleophilic c
โœ P. Perlmutter; M. Tabone ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 192 KB

Nucleophilic conjugate addition of benzylamine to 2-hydroxyalkylpropenoates la-c proceeds in high yield with modest diastereoselection. However, addition of benxylamine to the silyl ether of lc produces only the anti-isomer 2d in high yield Although nucleophilic conjugate additions of amines to 2-su