The title compound, commonly known as lidocaine, C 14 H 22 N 2 O, is a well known drug with local anaesthetic and anti-arrhythmic properties. Its structure has been reported previously, based on data of limited quality [Hanson & Banner (1974), Acta Cryst. B30, 2486-2488]. Results from a data collect
2-Chloro-N-methylacetamide revisited: a low-temperature study
✍ Scribed by Sousa, Alvaro S. de ;Marques, Helder M. ;Fernandes, Manuel A.
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 403 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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Rate constants, k, were determined for the solvolytic reactions of 2-bromo-2-methylbutane, 2-chloro-2methylbutane and 3-chloro-3-methylpentane in 10 pure diols at 298.15 K. The Gibbs energies of activation were calculated in order to study the influence of the solvent and to provide mechanistic info