2-chloro-2′-deoxyadenosine in the treatment of Sjögren's syndrome–associated B cell lymphoproliferation
✍ Scribed by Michalis Voulgarelis; George Petroutsos; Haralampos M. Moutsopoulos; Fotini N. Skopouli
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 168 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0004-3591
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## Objective: In patients with sjögren's syndrome (ss), b lymphocytes have been found to infiltrate salivary glands, resulting in sialadenitis and keratoconjunctivitis. the disease is frequently associated with benign and neoplastic lymphoproliferation. the present study was undertaken to investiga
Sjögren's syndrome (SS) represents a pathological model of the evolution from polyclonal B lymphocyte activation to oligoclonal/monoclonal B cell expansion, which may culminate in the development of a malignant lymphoproliferative disease. The different phases of this process are usually marked by t