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2-Benzyloxymethyl-5-(tributylstannyl)tetrazole. A reagent for the preparation of 5-aryl- and 5-heteroaryl-1H-tetrazoles via the Stille reaction

โœ Scribed by Brett C Bookser


Book ID
108379680
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
158 KB
Volume
41
Category
Article
ISSN
0040-4039

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Copper-catalyzed synthesis of 5-substitu
โœ Tienan Jin; Fukuzou Kitahara; Shin Kamijo; Yoshinori Yamamoto ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 135 KB

The [3+2] cycloaddition between various nitriles and trimethylsilyl azide proceeds smoothly in the presence of a Cu I catalyst in DMF/ MeOH, to give the corresponding 5-substituted 1H-tetrazoles in good to high yields. The reaction most probably proceeds through the in situ formation of a copper azi