Cover Picture: 2-Anilinobenzamides as SI
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Takayoshi Suzuki; Keiko Imai; Hidehiko Nakagawa; Naoki Miyata
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Article
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2006
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John Wiley and Sons
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English
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The cover picture shows the model of a SIRT inhibitor, 2βanilinobenzamide, bound to the catalytic core of a SIRT homologue. SIRTs catalyze the deacetylation of several proteins such as histones, p53, and Ξ³βtubulin, and are involved in certain disease states including cancer. SIRT inhibitors can be c