𝔖 Bobbio Scriptorium
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2-Anilinobenzamides as SIRT Inhibitors

✍ Scribed by Takayoshi Suzuki; Keiko Imai; Hidehiko Nakagawa; Naoki Miyata


Book ID
102101044
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
276 KB
Volume
1
Category
Article
ISSN
1860-7179

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Cover Picture: 2-Anilinobenzamides as SI
✍ Takayoshi Suzuki; Keiko Imai; Hidehiko Nakagawa; Naoki Miyata πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 35 KB

The cover picture shows the model of a SIRT inhibitor, 2‐anilinobenzamide, bound to the catalytic core of a SIRT homologue. SIRTs catalyze the deacetylation of several proteins such as histones, p53, and γ‐tubulin, and are involved in certain disease states including cancer. SIRT inhibitors can be c