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2- and 4-Nitrobenzenesulfonamides: Exceptionally versatile means for preparation of secondary amines and protection of amines

✍ Scribed by Tohru Fukuyama; Chung-Kuang Jow; Mui Cheung

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
116 KB
Volume
36
Category
Article
ISSN
0040-4039

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2,4-Dinitrobenzenesulfonamides, readily prepared from primary amines and 2,4-dinitrobenzenesulfonyl chloride, can be alkylated by the Mitsunobu reaction or by the conventional methods to give N,N-disubstituted sulfonamides in excellent yields. Since 2,4-dinitrobenzenesulfonamides can be removed with