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2-Amino-7-phosphonoheptanoic acid (2-APH) infusion into entopeduncular nucleus protects against limbic seizures in rats

✍ Scribed by Patel, Smita; Millan, M.-H.; Mello, L.M.; Meldrum, B.S.


Book ID
123489594
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
288 KB
Volume
64
Category
Article
ISSN
0304-3940

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Effect of 2-amino-7-phosphonoheptanoic a
✍ Gregory L. Holmes; James L. Thompson; G. Franklin Carl; Brian S. Gallagher; Jeff πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 English βš– 488 KB

There is now considerable evidence that the N-methyl-D-aspartic acid receptor is important in the genesis of seizures. One of the selective antagonist of the NMDA receptor is 2-amino-7-phosphonoheptanoic acid (APH). In this study we evaluated the effects of intracerebroventricular (i.c.v.) administr