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2-Amino-4H-3,1-benzoxazin-4-ones as Inhibitors of C1r Serine Protease

✍ Scribed by Hays, Sheryl J.; Caprathe, Bradley W.; Gilmore, John L.; Amin, Nilam; Emmerling, Mark R.; Michael, Walter; Nadimpalli, Ravi; Nath, Rathna; Raser, Kadee J.; Stafford, Daniel


Book ID
115501980
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
114 KB
Volume
41
Category
Article
ISSN
0022-2623

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Ring Opening of 2-(Benzylamino)-2H-1,4-b
✍ Janez IlaΕ‘; Danijel Kikelj πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 German βš– 223 KB πŸ‘ 1 views

## Abstract Substituted 2‐(benzylamino)‐2__H__‐1,4‐benzoxazin‐3(4__H__)‐ones are unstable under alkaline and acidic conditions, undergoing opening of the benzoxazinone ring. 2‐Bromo‐2__H__‐1,4‐benzoxazin‐3(4__H__)‐ones show similar degradation under alkaline conditions, while replacement of Br at C