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2-Amino-3-cyano-4-(5-arylisoxazol-3-yl)-4H-chromenes: Synthesis and In Vitro Cytotoxic Activity

✍ Scribed by Tahmineh Akbarzadeh; Ali Rafinejad; Javad Malekian Mollaghasem; Maliheh Safavi; Asal Fallah-Tafti; Mahboobeh Pordeli; Sussan Kabudanian Ardestani; Abbas Shafiee; Alireza Foroumadi

Book ID: 112002470
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 191 KB
Volume: 345
Category: Article
ISSN: 0365-6233
DOI: 10.1002/ardp.201100345

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## Abstract A new series of 4‐aryl‐4__H__‐chromenes bearing a 2‐arylthiazol‐4‐yl moiety at the 4‐position were prepared as potential cytotoxic agents. The __in‐vitro__ cytotoxic activity of the synthesized 4‐aryl‐4__H__‐chromenes was investigated in comparison with etoposide, a well‐known anticance