SAR Studies on the Potent and Selective
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Serena Scapecchi; Piero Angeli; Silvia Dei; Carla Ghelardini; Fulvio Gualtieri;
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Article
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1997
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John Wiley and Sons
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English
β 542 KB
Molecular modification of the potent and selective muscarinic antagonist 2-ethylthio-2,2-diphenylacetic acid N,N-diethylaminoethyl ester was performed in order to identify M2 selective antagonists able to cross the blood brain barrier and potentially useful in the treatment of Alzheimer's disease. M