The title compound, C 18 H 12 F 3 N 3 OS 2 , was synthesized by the reaction of [(Z)-1-phenylmethylidene]{5-[3-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl}amine and mercaptoacetic acid. In the structure there are intramolecular C-HÁ Á ÁS and C-HÁ Á ÁN and intermolecular C-HÁ Á ÁN hydrogen bonds.
2-[(4,5-Dihydro-4-phenylthiazol-2-yl)methyl]-3H-imidazo[4,5-b]pyridine
✍ Scribed by Sun, Ya-Wei ;Duan, Gui-Yun ;Liu, Jun-Zhi ;Meng, Li-Juan ;Wang, Jian-Wu
- Publisher
- International Union of Crystallography
- Year
- 2005
- Tongue
- English
- Weight
- 196 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1600-5368
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Single-crystal X-ray study T = 293 K Mean '(C±C) = 0.003 A Ê R factor = 0.040 wR factor = 0.116 Data-to-parameter ratio = 15.4 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
In the title compound, C 19 H 22 ClN 4 O 5 PS, the P atom adopts a distorted tetrahedral configuration. Intra-and intermolecular C-HÁ Á ÁO hydrogen bonds, together with weak C-HÁ Á Á hydrogen bonding and strongstacking interactions, stabilize the crystal structure.
The title compound, C 17 H 12 ClN 5 S, has been synthesized as a potent anticancer agent. The dihedral angle between the thiazole and triazole rings is 85.9 (2) . There are intermolecular N-HÁ Á ÁN and C-HÁ Á ÁCl interactions in the crystal structure.
Single-crystal X-ray study T = 293 K Mean '(C±C) = 0.004 A Ê R factor = 0.043 wR factor = 0.129 Data-to-parameter ratio = 12.7 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.