## Abstract (E)-3-{5-[3-(Trifluoromethyl)phenyl]furan-2-yl}propenoic acid (I) was prepared from 5-[3-(tri-fluoromethyl)phenyl]furan-2-carbaldehyde under the Doebner’s conditions. The obtained acid was converted to the corresponding azide II, which was cyclized by heating in diphenyl ether to 2-[3-(
✦ LIBER ✦
2-[3-(Trifluoromethyl)phenyl]furo[3,2-b]pyrroles: synthesis and reactions
✍ Scribed by Gajdoš, Peter ;Pavlíková, Soňa ;Bureš, Filip ;Krutošíková, Alžbeta
- Book ID
- 111487702
- Publisher
- Walter de Gruyter GmbH
- Year
- 2005
- Tongue
- English
- Weight
- 291 KB
- Volume
- 3
- Category
- Article
- ISSN
- 2391-5420
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## Abstract 2-[3-(Trifluoromethyl)phenyl]-4,5-dihydrofuro[3,2-c]pyridin-4-one (I) was prepared by a three-step synthesis. Its reaction with phosphorus sulfide rendered thione II which was methylated to 2-[3-(Trifluoromethyl)phenyl]-4-methylsulfanylfuro[3,2-c]pyridine (III). 5-Methyl-2-[3-(trifluoro
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