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2-(2-Oxo-1,4-dihydro-2 H -quinazolin-3-yl)- and 2-(2,2-Dioxo-1,4-dihydro-2 H -2λ 6 -benzo[1,2,6]thiadiazin-3-yl)- N -hydroxy-acetamides as Potent and Selective Peptide Deformylase Inhibitors

✍ Scribed by Apfel, Christian; Banner, David W.; Bur, Daniel; Dietz, Michel; Hubschwerlen, Christian; Locher, Hans; Marlin, Frédéric; Masciadri, Raffaello; Pirson, Wolfgang; Stalder, Henri

Book ID: 126133494
Publisher: American Chemical Society
Year: 2001
Tongue: English
Weight: 156 KB
Volume: 44
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm000352g

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## Abstract Two new structurally isomeric, 2‐(2,4,4‐trimethyl‐3,4‐dihydro‐2__H__‐benzo[__h__]chromen‐2‐yl)‐1‐naphthol (**1****)** and 3‐(2,4,4‐trimethyl‐3,4‐dihydro‐2__H__‐benzo[__g__]chromen‐2‐yl)‐2‐naphthol (**3**) have been synthesized from 2‐acetyl‐1‐naphthol and ethyl‐3‐hydroxy‐2‐naphthoate, r