1α,25-Dihydroxyvitamin D3 inhibits neutrophil recruitment in hamster model of acute lung injury
✍ Scribed by Yasuhiro Takano; Hiroaki Mitsuhashi; Koichi Ueno
- Book ID
- 116892659
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 779 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0039-128X
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## Abstract 9__‐cis__‐Retinoic acid (9cRA) and 1α,25‐dihydroxyvitamin D~3~ (1,25D) show promise as potential chemopreventive agents. We examined 9cRA and 1,25D, alone and in combination, for their potential to inhibit carcinogen (NNK)‐induced lung carcinogenesis in A/J mice. A/J mice (__n__ = 14/gr
Five analogs of 1 alpha,25-dihydroxyvitamin D3 [1,25(OH)2D3] [1], 26,27-dimethyl-1 alpha,25-dihydroxyvitamin D3 [1,25(OH)2(Me)2D3] [2], 26,27-dimethyl-1 alpha,25-dihydroxyvitamin D3 [1,25(OH)2(Et)2D3] [3], 26,27-dipropyl-1 alpha,25-dihydroxyvitamin D3 [1,25(OH)2(Pr)2D3] [4], 26,27-dimethyl-24,24-dif