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1α,25-dihydroxyvitamin D3 inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection

✍ Scribed by Anna Coussens; Peter M. Timms; Barbara J. Boucher; Timothy R. Venton; Anthony T. Ashcroft; Keira H. Skolimowska; Sandra M. Newton; Katalin A. Wilkinson; Robert N. Davidson; Christopher J. Griffiths; Robert J. Wilkinson; Adrian R. Martineau


Book ID
108782498
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
346 KB
Volume
127
Category
Article
ISSN
0019-2805

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1a,25-dihydroxyvitamin D 3 (VD 3 ) is a neuroprotectant that can reduce cytotoxicity produced by a variety of toxicants. The mechanism of the neuroprotection was studied in rat primary cortical cells in which Wy14,643, an agonist of peroxisome proliferator activated receptora (PPARa), enhances cyani