(1S,3R,6S,7R)-3,7-Dichloro-trans-himachalane
β Scribed by Ourhriss, Najia ;Mazoir, Noureddine ;Daran, Jean-Claude ;Berraho, Moha ;Benharref, Ahmed
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 229 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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β¦ Synopsis
The molecule of the title compound, C~15~H~26~Cl~2~, is built up from two fused six-membered and seven-membered rings. The six-membered ring has a perfect chair conformation, whereas the seven-membered ring displays a twist-chair conformation. A weak CβH...Cl hydrogen-bonding interaction links the molecule into a chain parallel to the a axis.
π SIMILAR VOLUMES
Mo K radiation = 0.25 mm Γ1 T = 180 (2) K 0.65 Γ 0.24 Γ 0.21 mm Data collection Oxford Diffraction Xcalibur CCD diffractometer Absorption correction: multi-scan (CrysAlis RED; Oxford Diffraction, 2006) T min = 0.756, T max = 1.000 (expected range = 0.718-0.950) 23369 measured reflections 6222 indepe
Quassiols A were synthesized enantioselectively by using baker's yeast reduction and asymmetric dihydroxylation, but their optical properties were not identical to that of natural quassiol A. Stereostructure of natural quassiol A was proposed.
The title compounds have been synthesized by using acetylenit coupling procedures, asymmetric epoxidation and stereo-and regio-selective openings of the epoxides.
**(+)β(1__S__, 3__S__, 6__S__, 8__S__)β and (β)β(1__R__, 3__R__, 6__R__, 8__R__)β2,7βdioxaβtwistaβ4,9βdiene.** A synthesis and the determination of the sense of chirality of (+)β(1__S__, 3__S__, 6__S__, 8__S__)β and (β)β(1__R__, 3__R__, 6__R__, 8__R__)β2,7βdioxaβtwistaβ4,9βdiene ((+)β**5** and (β)β