𝔖 Bobbio Scriptorium
✦   LIBER   ✦

(1′R,3S)-2-Oxo-1-(1′-phenyl­ethyl)­piperidine-3-carboxylic acid: a case of a very strong intramolecular hydrogen bond

✍ Scribed by Lumbreras-García, Ana-María ;Galindo-Guzmán, Alberto ;Gnecco, Dino ;Terán, Joel-Luis ;Bernès, Sylvain


Publisher
International Union of Crystallography
Year
2004
Tongue
English
Weight
183 KB
Volume
60
Category
Article
ISSN
1600-5368

No coin nor oath required. For personal study only.

✦ Synopsis


The title compound, C 14 H 17 NO 3 , exhibits a very strong C OÁ Á ÁHÐO intramolecular hydrogen bond, characterized by an OÁ Á ÁH separation of 1.39 (7) A Ê and an OÐHÁ Á ÁO angle of 153 (5) .


📜 SIMILAR VOLUMES


Synthesis of 14C-labeled 3-{[1-ethoxycar
✍ Naba K. Chaudhuri; Russell Patera; Bohdan Markus; Ming-Sang Sung 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 334 KB

The title compound, CGS 148248, was synthesized with a '%-label in the azepine ring in 14 steps starting with l-bromo-3-phenylpropane (1> and K1%N in an overall yield of 1.31%. The reaction of I with K 1 k N yielded the nitrile 2 which upon hydrolysis followed by ring closure gave a-tetral~ne-l-~~c

A simple synthesis of 5-ethoxycarbonyl-6
✍ Ahmet Şener; Hasan Genç; M. Kasimşener; Yüzüncü Yil 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 40 KB

## Abstract 4‐Ethoxycarbonyl‐5‐phenyl‐2,3‐dihydrofuran‐2,3‐dione **1** reacts with aldehydes __via__ the acylketene intermediate **2** giving the 1,3‐dioxin‐4‐ones **3a‐e** and the 1,4‐bis(5‐ethoxycarbonyl‐4‐oxo‐6‐phenyl‐4__H__‐1,3‐dioxin‐2‐yl)benzene **4**, and a one step reaction between dibenzoy

N,N′-Bis­[(R)-2-hydroxy-2-phenyl­ethyl]-
✍ Sosa-Rivadeneyra, Martha ;Quintero, Leticia ;Parrodi, Cecilia Anaya de ;Juaristi 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 271 KB

The title compound, C 39 H 39 N 3 O 4 , although having potential C 2 molecular symmetry, crystallizes as an asymmetric conformer, due to a couple of strong intramolecular hydrogen bonds involving hydroxyl groups and a pyridine N atom. This geometrical feature explains why this compound behaves as a