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1.P.274 Identification of a new mutation in exon 4 of the low density lipoprotein receptor gene in patients with familial hypercholesterolemia in Spain

✍ Scribed by J.C. Vallvé; C. Alonso-Villaverde; J. Margalef; J. Ribalta; L. Masana


Book ID
119437320
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
191 KB
Volume
134
Category
Article
ISSN
0021-9150

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Elevated blood plasma cholesterol (hypercholesterolemia) is a major risk factor for coronary artery disease (CAD) in humans. Genetic dissection of polygenic lipid and lipoprotein disorders in swine, a key animal model for the study of familial hypercholesterolemia (FH) and CAD, led to the isolation