𝔖 Bobbio Scriptorium
✦   LIBER   ✦

1H,13C, 19F NMR, and ESI mass spectral characterization of two geminal difluorosteroids

✍ Scribed by Elina Sievänen; Virpi Noponen; Vladimír Král; Tomáš Bříza; Erkki Kolehmainen

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
127 KB
Volume
46
Category
Article
ISSN
0749-1581

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Two geminal difluorosteroids, 3,3‐difluoro‐5β‐cholan‐24‐oic acid (1) and 3,3‐difluoro‐5α‐androstan‐17‐one (2), have been prepared from corresponding ketosteroids with diethylaminosulphurtrifluoride (DAST) treatment in moderate yields. The structures of 1 and 2 have been characterized by ^1^H, ^13^C, ^19^F NMR, and ESI mass spectral techniques. Copyright © 2008 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

1H, 13C and 19F NMR spectral data for fi
1H, 13C and 19F NMR spectral data for fifteen fluorinated steroids
✍ Janis T. Nelson; Lilia J. Kurz 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 319 KB

## Abstract Analyses of the ^1^H, ^13^C and ^19^F NMR spectra of 15 mono‐, di‐, tri‐ or tetrafluoro‐substituted steroids were carried out by two‐dimensional ^1^H^1^H and ^1^H^13^C shift correlation experiments.

1H, 19F and 13C NMR spectral data of fif
1H, 19F and 13C NMR spectral data of fifteen gyrase inhibitors and some metabolites
✍ Ulrike Holzgrabe; Sarah K. Branch 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 311 KB

## Abstract Analyses of ^1^H and ^13^C NMR spectra of 15 gyrase inhibitors were carried out using mainly the hydrogen—fluorine and the carbon‐fluorine coupling constants. ^19^F NMR chemical shifts were obtained for pefloxacin and its metabolites.

1H, 13C, 19F and 11B NMR spectral refere
1H, 13C, 19F and 11B NMR spectral reference data of some potassium organotrifluoroborates
✍ Roberta A. Oliveira; Ricardo O. Silva; Gary A. Molander; Paulo H. Menezes 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB

## Abstract Complete ^1^H, ^13^C, ^19^F and ^11^B NMR spectral data for 28 potassium organotrifluoroborates are described. The resonance for the carbon bearing the boron atom is described for most of the studied compounds. A modified ^11^B NMR pulse sequence was used and better resolution was obser

Characterization of monofluorinated poly
Characterization of monofluorinated polycyclic aromatic compounds by 1H, 13C and 19F NMR spectroscopy
✍ Bjart Frode Lutnaes; Gregor Luthe; Udo A. Th. Brinkman; Jon E. Johansen; Jostein 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB

## Abstract Monofluorinated polycyclic aromatic hydrocarbons (F‐PAHs) have attracted much attention in analytical, environmental, toxicological and mechanistic studies because of their physico‐chemical properties, which are closely similar to those of the parent PAHs. Because of this, full NMR char

1H and 13C NMR spectral assignments and
1H and 13C NMR spectral assignments and conformational analysis of 14 19-nor-neoclerodane diterpenoids
✍ Benjamín Rodríguez; María L. Jimeno 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

## Abstract Unambiguous and complete assignments of ^1^H and ^13^C NMR chemical shifts for 14 19‐nor‐neoclerodane diterpenoids, nine of them isolated from natural sources and five other synthetic derivatives, are presented. The assignments are based on 2D shift‐correlated (^1^H,^1^H‐COSY, ^1^H,^13^