𝔖 Bobbio Scriptorium
✦   LIBER   ✦

1H NMR study of cyclo-L-Thr-L-Thr and cyclo-L-Thr-L-His conformations

✍ Scribed by Marius Ptak; Annie Heitz

Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
191 KB
Volume
6
Category
Article
ISSN
0749-1581

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Cyclodipeptides containing L‐Thr and L‐His residues have been studied by ^1^H NMR in D~2~O and DMSO‐d~6~. In the neutral form in D~2~O as in DMSO‐d~6~, the folded form of the L‐His residue is not unique. The diketopiperazine ring seems to be not strictly planar.

📜 SIMILAR VOLUMES

Solution conformation and hydrolytic act
Solution conformation and hydrolytic activity of cyclo(D-leu-L-His)
✍ Masao Tanihara; Yukio Imanishi; Toshinobu Higashimura 📂 Article 📅 1977 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 631 KB

## Abstract It has been reported previously that a cyclic dipeptide, cyclo(D‐Leu‐L‐His), showed a high hydrolytic activity toward a hydrophobic ester, __p__‐nitrophenyl laurate. In order to determine the reason for the high catalytic activity, the conformation of cyclo(D‐Leu‐L‐His) in aqueous solut

Hormone-Receptor Interactions. Synthesis
Hormone-Receptor Interactions. Synthesis and Conformational Study of cyclo-L-Cystathionine
✍ Jean-Luc Fauchère; Natesa Muthukumaraswamy; Aung Tun-Kyi; Robert Schwyzer 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 German ⚖ 493 KB

## Abstract The purpose of this work was to see whether the replacement of a sulfur atom in a cystine disulfide bridge by a methylene group is an only superficial ‘isosteric’ substitution, __i.e.__ with regard to size, hydrophobia, bond angles, __etc.__, or whether it would also encompass such para

Conformation and formation tendency of t
Conformation and formation tendency of the cyclotetrapeptide cyclo(D-pro-D-pro-L-pro-L-pro): Experimental results and molecular modeling studies
✍ Werner Mästle; Ulrich Link; Wolfgang Witschel; Ulf Thewalt; Thomas Weber; Manfre 📂 Article 📅 1991 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 787 KB

The title compound represents the smallest member of cyclic proline peptides corresponding to the general formula c ( DDLL-Pro,), with a strictly D,D,L,L double-alternating sequence of the chiral amino acid residues. The cyclopeptides with n 2 2 could be synthesized from both DDLL-Pro4 ( 1 ) and DLL