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1H-NMR studies of postmortem biochemical changes in rat skeletal muscle

✍ Scribed by V. Fineschi; M.P. Picchi; M. Tassini; G. Valensin; A. Vivi

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
632 KB
Volume
44
Category
Article
ISSN
0379-0738

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✦ Synopsis

1H-nuclear magnetic resonance (NMR) has been applied to the study of postmortem biochemical changes in perchloric acid extracts of rat skeletal muscle. Several metabolites have been detected and the dependence upon the postmortem time has been considered. The simultaneous quantitative determination of metabolites showing up at very low and very high fields has been suggested to yield a satisfactory delineation of the thanatochronology.

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## Abstract Non‐isotropic contributions to ^1^H MR spectra from human skeletal muscle __in vivo__ have recently been observed in the 0‐to 5‐ppm region. One pair of peaks has been identified to be subject to dipolar couplings. The corresponding changes in resonance frequency are related to the orien