1H NMR investigation of self-association of aromatic drug molecules in aqueous solution. Structural and thermodynamical analysis
โ Scribed by Davies, David B.; Djimant, Leonid N.; Veselkov, Alexei N.
- Book ID
- 120609297
- Publisher
- Royal Society of Chemistry
- Year
- 1996
- Tongue
- English
- Weight
- 1023 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0956-5000
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๐ SIMILAR VOLUMES
The complexation of antitumour antibiotics novatrone (NOV) and daunomycin (DAU) in aqueous solution has been studied by one-and two-dimensional 1 H-NMR spectroscopy (500 MHz) in order to elucidate the probable molecular mechanism of the action of aromatic antitumour drugs in combination chemotherapy
The hetero-association of theophylline (THP) with other biologically-active aromatic molecules (e.g. the anti-cancer drugs daunomycin and novantrone, the antibiotic norfloxacin, the vitamin flavin-mononucleotide and two mutagens ethidium bromide and proflavine) has been studied by NMR in aqueous-sal