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1H NMR Detection of σ-Adducts inSNH Reactions of Nitroquinolines with Chloromethyl Phenyl Sulfone

✍ Scribed by M. A. Grzegozek


Book ID
110391630
Publisher
Springer US
Year
2002
Tongue
English
Weight
112 KB
Volume
38
Category
Article
ISSN
0009-3122

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Regioselectivity in SNH Reactions of Nit
✍ Grzegożek, Maria ;Woźniak, Marian ;van der Plas, Henk C. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 333 KB

## Abstract 3‐Nitro‐, 4‐nitro‐, 7‐nitro‐, 5,7‐dinitro‐, and 6,8‐dinitroquinoline react with the carbanion of chloromethyl phenyl sulfone to give products of substitution of hydrogen at positions 4, 3, 8, 6,8, and 5,7, respectively. The reactions are found by quantum chemical calculations to be cont